Description
| Antibody Name: | Angptl8 Antibody (PACO39174) |
| Antibody SKU: | PACO39174 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Betatrophin protein (16-198AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Hormone that specifically promotes pancreatic β cell proliferation and β cell mass expansion, thereby improving glucose tolerance. Promotes pancreatic β cell proliferation without insulin resistance. Also acts as a blood lipid regulator by regulating serum triglyceride levels; possibly by promoting ANGPTL3 cleavage. |
| Synonyms: | Angiopoietin-like protein 8 (Betatrophin) (Lipasin) (Refeeding-induced fat and liver protein), Angptl8, Gm6484 Rifl |
| UniProt Protein Function: | EG624219: Hormone that specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. Promotes pancreatic beta cell proliferation without insulin resistance. Also acts as a blood lipid regulator by regulating serum triglyceride levels; possibly by promoting ANGPTL3 cleavage. In response to food intake. Interacts with ANGPTL3 |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 9|9 A3 Cellular Component: extracellular region Molecular Function:hormone activity Biological Process: cell maturation; cellular lipid metabolic process; fat cell differentiation; glucose metabolic process; negative regulation of lipoprotein lipase activity; regulation of lipid metabolic process; regulation of lipoprotein metabolic process |
| UniProt Code: | Q8R1L8 |
| NCBI GenInfo Identifier: | 124301204 |
| NCBI Gene ID: | 624219 |
| NCBI Accession: | NP_001074409.1 |
| UniProt Related Accession: | Q8R1L8 |
| Molecular Weight: | 22.5kD |
| NCBI Full Name: | angiopoietin-like protein 8 |
| NCBI Synonym Full Names: | angiopoietin-like 8 |
| NCBI Official Symbol: | Angptl8 |
| NCBI Official Synonym Symbols: | Rifl; Gm6484; EG624219 |
| NCBI Protein Information: | angiopoietin-like protein 8 |
| UniProt Protein Name: | Angiopoietin-like protein 8 |
| UniProt Synonym Protein Names: | Betatrophin |
| UniProt Gene Name: | Angptl8 |