ANAPC15 Antibody (PACO08072)
- SKU:
- PACO08072
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ANAPC15 Antibody (PACO08072) |
| Antibody SKU: | PACO08072 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human C11orf51 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | chromosome 11 open reading frame 51;C11orf51;DKFZp564M082;HSPC020 ; |
| UniProt Protein Function: | APC15: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20. Belongs to the APC15 family.Chromosomal Location of Human Ortholog: 11q13.4Cellular Component: anaphase-promoting complex; cytosol; intracellular; nucleoplasmBiological Process: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination during ubiquitin-dependent protein catabolic process; regulation of ubiquitin-protein ligase activity during mitotic cell cycle |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P60006 |
| NCBI GenInfo Identifier: | 511094008 |
| NCBI Gene ID: | 25906 |
| NCBI Accession: | NP_001265414.1 |
| UniProt Secondary Accession: | P60006,Q9CXK2, Q9Y269, G3V1Q3 |
| UniProt Related Accession: | P60006 |
| Molecular Weight: | 41.7kD |
| NCBI Full Name: | anaphase-promoting complex subunit 15 isoform a |
| NCBI Synonym Full Names: | anaphase promoting complex subunit 15 |
| NCBI Official Symbol: | ANAPC15 |
| NCBI Official Synonym Symbols: | APC15; HSPC020; C11orf51 |
| NCBI Protein Information: | anaphase-promoting complex subunit 15 |
| UniProt Protein Name: | Anaphase-promoting complex subunit 15 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Anaphase-promoting complex |
| UniProt Gene Name: | ANAPC15 |
| UniProt Entry Name: |
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