Description
| Product Name: | Amylin/DAP Monoclonal Antibody |
| Product Code: | CAB24014 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62989 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293F-IAPP |
| Cellular Location: | Secreted |
This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 34-70 of human Amylin/DAP (NP_000406.1). |
| Sequence: | MGILK LQVFL IVLSV ALNHL KATPI ESHQV EKRKC NTATC ATQRL ANFLV HSSNN FGAIL SSTNV GSNTY GKRNA VEVLK REPLN YLPL |
| Synonyms: | DAP, IAP |
| Calculated MW: | 10kDa |
| Observed MW: | 35kDa |