AMTN Antibody (PACO24896)
- SKU:
- PACO24896
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | AMTN Antibody (PACO24896) |
| Antibody SKU: | PACO24896 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Amelotin protein (17-209AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO24896 at dilution of 1:100. |
| Background: | Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis. |
| Synonyms: | Amelotin, AMTN |
| UniProt Protein Function: | AMTN: Could be a cell adhesion protein involved in the maturation of tooth enamel. Belongs to the amelotin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Extracellular matrix; Secreted; Secreted, signal peptide; Cell adhesionChromosomal Location of Human Ortholog: 4q13.3Cellular Component: basal lamina; intercellular junction; proteinaceous extracellular matrixBiological Process: odontogenesis of dentine-containing teeth |
| UniProt Protein Details: | |
| NCBI Summary: | The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q6UX39 |
| NCBI GenInfo Identifier: | 55976710 |
| NCBI Gene ID: | 401138 |
| NCBI Accession: | Q6UX39.1 |
| UniProt Secondary Accession: | Q6UX39,Q0P503, Q0P506 |
| UniProt Related Accession: | Q6UX39 |
| Molecular Weight: | 21,459 Da |
| NCBI Full Name: | Amelotin |
| NCBI Synonym Full Names: | amelotin |
| NCBI Official Symbol: | AMTN |
| NCBI Official Synonym Symbols: | UNQ689 |
| NCBI Protein Information: | amelotin |
| UniProt Protein Name: | Amelotin |
| UniProt Synonym Protein Names: | |
| Protein Family: | Amelotin |
| UniProt Gene Name: | AMTN |
| UniProt Entry Name: | AMTN_HUMAN |
Related Products
HS3ST3B1 Antibody
Overview Product Name:HS3ST3B1 AntibodyProduct Code:PACO64781Size:50µLTarget Names:HS3ST3B1Species Reactivity:Human<
hns Antibody
Overview Product Name:hns AntibodyProduct Code:PACO64777Size:50µLTarget Names:hnsSpecies Reactivity:Escherichia coli
Avpr1b Antibody
Overview Product Name:Avpr1b AntibodyProduct Code:PACO64609Size:50µLTarget Names:Avpr1bSpecies Reactivity:RatHos
SEZ6 Antibody
Overview Product Name:SEZ6 AntibodyProduct Code:PACO64941Size:50µLTarget Names:SEZ6Species Reactivity:HumanHost