AMPKα1 Polyclonal Antibody (CAB21813)
_WB_01__38960__37731.1706547121.jpg?c=1 "AMPKα1 Polyclonal Antibody (CAB21813)")
- SKU:
- CAB21813
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Isotype:
- IgG
- Applications:
- WB
_WB_01__38960__37731.1706547121.jpg?c=1&imbypass=on "AMPKα1 Polyclonal Antibody (CAB21813)")
Description
| Product Name: | AMPKα1 Polyclonal Antibody |
| Product Code: | CAB21813 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse liver |
| Cellular Location: | apical plasma membrane, cytoplasm, cytosol, nuclear speck, nucleoplasm, nucleus |
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human AMPKα1 (NP_006242.5). |
| Sequence: | IFMVM EYVSG GELFD YICKN GRLDE KESRR LFQQI LSGVD YCHRH MVVHR DLKPE NVLLD AHMNA KIADF GLSNM MSDGE FLRTS CGSPN YAAPE VISGR L |
| Synonyms: | AMPK, AMPKa1, AMPK alpha 1 |
| Calculated MW: | 64kDa |
| Observed MW: | 64kDa |
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