AMPKα1 Polyclonal Antibody (CAB21813)

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SKU:
CAB21813

Description

Product Name:AMPKα1 Polyclonal Antibody
Product Code:CAB21813
Reactivity:Mouse
Applications:Western blotting
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Mouse
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:100-1:500
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Positive Samples:Mouse liver
Cellular Location:apical plasma membrane, cytoplasm, cytosol, nuclear speck, nucleoplasm, nucleus

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human AMPKα1 (NP_006242.5).
Sequence:IFMVM EYVSG GELFD YICKN GRLDE KESRR LFQQI LSGVD YCHRH MVVHR DLKPE NVLLD AHMNA KIADF GLSNM MSDGE FLRTS CGSPN YAAPE VISGR L
Synonyms:AMPK, AMPKa1, AMPK alpha 1
Calculated MW:64kDa
Observed MW:64kDa
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Additional Information

Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Isotype:
IgG
Applications:
WB
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