AMPKα1 Polyclonal Antibody (CAB21744)
- SKU:
- CAB21744
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IF
Description
| Product Name: | AMPKα1 Polyclonal Antibody |
| Product Code: | CAB21744 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | IF/ICC, ELISA |
| Key Applications: | Immunofluorescence |
| Recommended Dilution: | IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm, Nucleus |
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 450-559 of human AMPKα1 (NP_006242.5). |
| Sequence: | PVTST YSKMS LQLYQ VDSRT YLLDF RSIDD EITEA KSGTA TPQRS GSVSN YRSCQ RSDSD AEAQG KSSEV SLTSS VTSLD SSPVD LTPRP GSHTI EFFEM CANLI KILAQ |
| Synonyms: | AMPK, AMPKa1, AMPK alpha 1 |
| Calculated MW: | 64kDa |
| Observed MW: | Refer to figures |
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