AMIGO2 Antibody (PACO37286)
- SKU:
- PACO37286
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | AMIGO2 Antibody (PACO37286) |
| Antibody SKU: | PACO37286 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500 |
| Species Reactivity: | Human, Rat |
| Immunogen: | Recombinant Human Amphoterin-induced protein 2 protein (420-522AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Rat liver tissue. All lanes: AMIGO2 antibody at 3.2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 58 kDa. Observed band size: 58 kDa. |
 | IHC image of PACO37286 diluted at 1:800 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO37286 diluted at 1:800 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. |
| Synonyms: | Amphoterin-induced protein 2 (AMIGO-2) (Alivin-1) (Differentially expressed in gastric adenocarcinomas) (DEGA), AMIGO2, ALI1 |
| UniProt Protein Function: | Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q86SJ2 |
| NCBI GenInfo Identifier: | 219521831 |
| NCBI Gene ID: | 347902 |
| NCBI Accession: | NP_001137140.1 |
| UniProt Secondary Accession: | Q86SJ2,Q4VBP6, Q7Z4A0, Q96CN8 |
| UniProt Related Accession: | Q86SJ2 |
| Molecular Weight: | 57 |
| NCBI Full Name: | amphoterin-induced protein 2 |
| NCBI Synonym Full Names: | adhesion molecule with Ig like domain 2 |
| NCBI Official Symbol: | AMIGO2 |
| NCBI Official Synonym Symbols: | ALI1; DEGA; AMIGO-2 |
| NCBI Protein Information: | amphoterin-induced protein 2 |
| UniProt Protein Name: | Amphoterin-induced protein 2 |
| UniProt Synonym Protein Names: | AMIGO-2; Alivin-1; Differentially expressed in gastric adenocarcinomas; DEGA |
| Protein Family: | |
| UniProt Gene Name: | AMIGO2 |
| UniProt Entry Name: |
| Antibodies |
| AMIGO2 Antibody (PACO07715) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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