AMIGO1 Antibody (PACO37418)
- SKU:
- PACO37418
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | AMIGO1 Antibody (PACO37418) |
| Antibody SKU: | PACO37418 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Amphoterin-induced protein 1 protein (28-327AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human spleen tissue using PACO37418 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO37418 at dilution of 1:100. |
| Background: | Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. |
| Synonyms: | Amphoterin-induced protein 1 (AMIGO-1) (Alivin-2), AMIGO1, ALI2 AMIGO KIAA1163 |
| UniProt Protein Function: | AMIGO1: Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain. Belongs to the immunoglobulin superfamily. AMIGO family.Protein type: Cell development/differentiation; Membrane protein, integralChromosomal Location of Human Ortholog: 1p13.3Cellular Component: axon; dendrite; perikaryon; voltage-gated potassium channel complexMolecular Function: potassium channel regulator activityBiological Process: axonal fasciculation; axonogenesis; heterophilic cell adhesion; homophilic cell adhesion; myelination; positive regulation of axonogenesis; positive regulation of synaptogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q86WK6 |
| NCBI GenInfo Identifier: | 68052342 |
| NCBI Gene ID: | 57463 |
| NCBI Accession: | Q86WK6.1 |
| UniProt Secondary Accession: | Q86WK6,Q8IW71, Q9ULQ7, B4DIM3 |
| UniProt Related Accession: | Q86WK6 |
| Molecular Weight: | 55,239 Da |
| NCBI Full Name: | Amphoterin-induced protein 1 |
| NCBI Synonym Full Names: | adhesion molecule with Ig-like domain 1 |
| NCBI Official Symbol: | AMIGO1 |
| NCBI Official Synonym Symbols: | ALI2; AMIGO; AMIGO-1 |
| NCBI Protein Information: | amphoterin-induced protein 1 |
| UniProt Protein Name: | Amphoterin-induced protein 1 |
| UniProt Synonym Protein Names: | AMIGO-1; Alivin-2 |
| Protein Family: | |
| UniProt Gene Name: | AMIGO1 |
| UniProt Entry Name: | AMGO1_HUMAN |
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