ALG14 Antibody (PACO39582)
- SKU:
- PACO39582
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ALG14 Antibody (PACO39582) |
| Antibody SKU: | PACO39582 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human UDP-N-acetylglucosamine transferase subunit ALG14 homolog protein (25-216AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO39582 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO39582 at dilution of 1:100. |
| Background: | May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER. |
| Synonyms: | UDP-N-acetylglucosamine transferase subunit ALG14 homolog, ALG14 |
| UniProt Protein Function: | ALG14: May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER. Belongs to the ALG14 family.Protein type: Membrane protein, integral; Glycan Metabolism - N-glycan biosynthesisChromosomal Location of Human Ortholog: 1p21.3Cellular Component: endoplasmic reticulum membraneMolecular Function: N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activityBiological Process: dolichol-linked oligosaccharide biosynthetic processDisease: Myasthenic Syndrome, Congenital, Without Tubular Aggregates |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the glycosyltransferase 1 family. The encoded protein and ALG13 are thought to be subunits of UDP-GlcNAc transferase, which catalyzes the first two committed steps in endoplasmic reticulum N-linked glycosylation. Mutations in this gene have been linked to congenital myasthenic syndrome (CMSWTA). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015] |
| UniProt Code: | Q96F25 |
| NCBI GenInfo Identifier: | 74731649 |
| NCBI Gene ID: | 199857 |
| NCBI Accession: | Q96F25.1 |
| UniProt Secondary Accession: | Q96F25,A8K030 |
| UniProt Related Accession: | Q96F25 |
| Molecular Weight: | 24,151 Da |
| NCBI Full Name: | UDP-N-acetylglucosamine transferase subunit ALG14 homolog |
| NCBI Synonym Full Names: | ALG14, UDP-N-acetylglucosaminyltransferase subunit |
| NCBI Official Symbol: | ALG14 |
| NCBI Official Synonym Symbols: | CMS15 |
| NCBI Protein Information: | UDP-N-acetylglucosamine transferase subunit ALG14 homolog |
| UniProt Protein Name: | UDP-N-acetylglucosamine transferase subunit ALG14 homolog |
| UniProt Synonym Protein Names: | |
| Protein Family: | UDP-N-acetylglucosamine transferase |
| UniProt Gene Name: | ALG14 |
| UniProt Entry Name: | ALG14_HUMAN |
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