Description
Antibody Name: | ALG12 Antibody (PACO15385) |
Antibody SKU: | PACO15385 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse |
Immunogen: | Fusion protein of human ALG12 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15385(ALG12 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using PACO15385(ALG12 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. |
Synonyms: | ALG12, alpha-1,6-mannosyltransferase |
UniProt Protein Function: | |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9BV10 |
NCBI GenInfo Identifier: | 13129114 |
NCBI Gene ID: | 79087 |
NCBI Accession: | NP_077010 |
UniProt Secondary Accession: | Q9BV10 |
UniProt Related Accession: | Q9BV10 |
Molecular Weight: | 53kDa |
NCBI Full Name: | dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase |
NCBI Synonym Full Names: | ALG12 alpha-1,6-mannosyltransferase |
NCBI Official Symbol: | ALG12 |
NCBI Official Synonym Symbols: | CDG1G; ECM39; hALG12; PP14673 |
NCBI Protein Information: | dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase |
UniProt Protein Name: | Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase |
UniProt Synonym Protein Names: | Asparagine-linked glycosylation protein 12 homolog; hALG12; Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase; Mannosyltransferase ALG12 homolog; Membrane protein SB87 |
Protein Family: | |
UniProt Gene Name: | ALG12 |
UniProt Entry Name: | ALG12_HUMAN |