Description
| Antibody Name: | ALG12 Antibody (PACO15385) | 
| Antibody SKU: | PACO15385 | 
| Size: | 50ul | 
| Host Species: | Rabbit | 
| Tested Applications: | ELISA, IHC | 
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 | 
| Species Reactivity: | Human, Mouse | 
| Immunogen: | Fusion protein of human ALG12 | 
| Form: | Liquid | 
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | 
| Purification Method: | Antigen affinity purification | 
| Clonality: | Polyclonal | 
| Isotype: | IgG | 
| Conjugate: | Non-conjugated | 
![]()  | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15385(ALG12 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). | 
![]()  | The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using PACO15385(ALG12 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). | 
| Background: | This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. | 
| Synonyms: | ALG12, alpha-1,6-mannosyltransferase | 
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. [provided by RefSeq, Jul 2008] | 
| UniProt Code: | Q9BV10 | 
| NCBI GenInfo Identifier: | 13129114 | 
| NCBI Gene ID: | 79087 | 
| NCBI Accession: | NP_077010 | 
| UniProt Secondary Accession: | Q9BV10 | 
| UniProt Related Accession: | Q9BV10 | 
| Molecular Weight: | 53kDa | 
| NCBI Full Name: | dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase | 
| NCBI Synonym Full Names: | ALG12 alpha-1,6-mannosyltransferase | 
| NCBI Official Symbol: | ALG12 | 
| NCBI Official Synonym Symbols: | CDG1G; ECM39; hALG12; PP14673 | 
| NCBI Protein Information: | dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase | 
| UniProt Protein Name: | Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase | 
| UniProt Synonym Protein Names: | Asparagine-linked glycosylation protein 12 homolog; hALG12; Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase; Mannosyltransferase ALG12 homolog; Membrane protein SB87 | 
| Protein Family: | |
| UniProt Gene Name: | ALG12 | 
| UniProt Entry Name: | ALG12_HUMAN | 
            
