Aldehyde dehydrogenase 5-A1/SSADH/ALDH5A1 Monoclonal Antibody
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- SKU:
- CAB24829
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | Aldehyde dehydrogenase 5-A1/SSADH/ALDH5A1 Monoclonal Antibody |
| Product Code: | CAB24829 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC64127 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Caco-2, Mouse liver |
| Cellular Location: | Mitochondrion |
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 777-976 of human Aldehyde dehydrogenase 5-A1/SSADH/ALDH5A1(NP_001071.1). |
| Sequence: | LGGLA PFIVF DSANV DQAVA GAMAS KFRNT GQTCV CSNQF LVQRG IHDAF VKAFA EAMKK NLRVG NGFEE GTTQG PLINE KAVEK VEKQV NDAVS KGATV VTGGK RHQLG KNFFE PTLLC NVTQD MLCTH EETFG PLAPV IKFDT EEEAI AIANA ADVGL AGYFY SQDPA QIWRV AEQLE VGMVG VNEGL ISSVE CPFGG VKQSG LGREG SKYGI DEYLE LKYVC YGGL |
| Synonyms: | SSDH, SSADH |
| Calculated MW: | 57kDa |
| Observed MW: | 54kDa |
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