AKT2 Monoclonal Antibody

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SKU:
CAB24009
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IHC
Applications:
IF

Description

Product Name:AKT2 Monoclonal Antibody
Product Code:CAB24009
Reactivity:Human, Mouse, Rat
Applications:Western blotting, Immunohistochemistry, Immunofluorescence
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC62648
Reactivity:Human, Mouse, Rat
Tested Applications:WB, IHC-P, IF/ICC, ELISA
Key Applications:Western blotting, Immunohistochemistry, Immunofluorescence
Recommended Dilution:WB 1:1000-1:5000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Positive Samples:Jurkat, 293T, NIH/3T3, Mouse small intestine (Low expression control), Rat thymus, Rat brain (Low expression control)
Cellular Location:Cell membrane, Cytoplasm, Early endosome, Nucleus, Peripheral membrane protein

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The gene serves as an oncogene in the tumorigenesis of cancer cells For example, its overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins, and has also been implicated in insulin signaling.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 390-490 of human AKT2.
Sequence:AKEVM EHRFF LSINW QDVVQ KKLLP PFKPQ VTSEV DTRYF DDEFT AQSIT ITPPD RYDSL GLLEL DQRTH FPQFS YSASI RE
Synonyms:PKBB, PRKBB, HIHGHH, PKBBETA, RAC-BETA
Calculated MW:56kDa
Observed MW:60kDa
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