AKT2 Monoclonal Antibody
- SKU:
- CAB24009
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | AKT2 Monoclonal Antibody |
| Product Code: | CAB24009 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62648 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, 293T, NIH/3T3, Mouse small intestine (Low expression control), Rat thymus, Rat brain (Low expression control) |
| Cellular Location: | Cell membrane, Cytoplasm, Early endosome, Nucleus, Peripheral membrane protein |
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains, which is involved in signaling pathways. The gene serves as an oncogene in the tumorigenesis of cancer cells For example, its overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins, and has also been implicated in insulin signaling.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 390-490 of human AKT2. |
| Sequence: | AKEVM EHRFF LSINW QDVVQ KKLLP PFKPQ VTSEV DTRYF DDEFT AQSIT ITPPD RYDSL GLLEL DQRTH FPQFS YSASI RE |
| Synonyms: | PKBB, PRKBB, HIHGHH, PKBBETA, RAC-BETA |
| Calculated MW: | 56kDa |
| Observed MW: | 60kDa |
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