AKT1S1/PRAS40 Polyclonal Antibody (CAB6238)
- SKU:
- CAB6238
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | AKT1S1/PRAS40 Polyclonal Antibody |
| Product Code: | CAB6238 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:2000, IHC-P 1:50-1:100, IF/ICC 1:50-1:100 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse heart, Rat heart |
| Cellular Location: | Cytoplasm, cytosol |
AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-256 of human AKT1S1/PRAS40 (NP_001092103.1). |
| Sequence: | STDDG SLSEE TPAGP PTCSV PPASA LPTQQ YAKSL PVSVP VWGFK EKRTE ARSSD EENGP PSSPD LDRIA ASMRA LVLRE AEDTQ VFGDL PRPRL NTSDF QKLKR KY |
| Synonyms: | Lobe, PRAS40 |
| Calculated MW: | 27kDa |
| Observed MW: | 50kDa |
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