Description
| Product Name: | AKT1S1/PRAS40 Monoclonal Antibody |
| Product Code: | CAB3391 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC1965 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, MCF7, NIH/3T3, RD |
| Cellular Location: | Cytoplasm, cytosol |
AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-256 of human AKT1S1/PRAS40 (Q96B36). |
| Sequence: | STDDG SLSEE TPAGP PTCSV PPASA LPTQQ YAKSL PVSVP VWGFK EKRTE ARSSD EENGP PSSPD LDRIA ASMRA LVLRE AEDTQ VFGDL PRPRL NTSDF QKLKR KY |
| Synonyms: | Lobe, PRAS40 |
| Calculated MW: | 27kDa |
| Observed MW: | 40kDa |