AKR1C1 Monoclonal Antibody [PAT6D10AT] (CPAB0106)
![AKR1C1 Monoclonal Antibody [PAT6D10AT] (CPAB0106)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58332/63514/akr1c1-monoclonal-antibody-pat6d10at-cpab0106__23591__95956.1706534974.jpg?c=1 "AKR1C1 Monoclonal Antibody [PAT6D10AT] (CPAB0106)")
- SKU:
- CPAB0106
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT6D10AT
- Applications:
- WB
- Applications:
- ELISA
![AKR1C1 Monoclonal Antibody [PAT6D10AT] (CPAB0106)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58332/63514/akr1c1-monoclonal-antibody-pat6d10at-cpab0106__23591__95956.1706534974.jpg?c=1&imbypass=on "AKR1C1 Monoclonal Antibody [PAT6D10AT] (CPAB0106)")
Description
system_update_alt Datasheet
| Product Name: | AKR1C1 Antibody |
| Product Sku: | CPAB0106 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human AKR1C1 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human AKR1C1 amino acids 1-323 purified from Ecoli. |
| Clone: | PAT6D10AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | AKR1C1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG1 |
| Background: | AKR1C1 transfers progesterone to its inactive state or in other words catalyzes the reaction of 20-alpha-hydroxy progesterone (20-alpha-OHP). In the liver and intestine. AKR1C1 transfers bile and monitors the intrahepatic bile acid concentration though it has a low bile-binding ability. AKR1C1 participates in myelin formation. AKR1C1 is part of the aldo/keto reductase superfamily, which has over 40 known enzymes which catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors thus display overlapping but distinct substrate specificity. |
| Synonyms: | DDH1, DDH, HAKRC, 20-alpha-HSD, DD1/DD2, HBAB, C9, DD1, H-37, MBAB, MGC8954, 2-ALPHA-HSD, AKR1C1, Aldo-keto reductase family 1 member C1, 20-alpha-hydroxysteroid dehydrogenase, Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, Indanol dehydrogenase, Dihydrodiol dehydrogenase 1/2, Chlordecone reductase homolog HAKRC, High-affinity hepatic bile acid-binding protein. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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