AKIP1 Antibody (PACO23285)
- SKU:
- PACO23285
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | AKIP1 Antibody (PACO23285) |
| Antibody SKU: | PACO23285 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from internal of human BCA3. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from Jurkat cells, using BCA3 antibody. |
 | Immunohistochemistry analysis of paraffin-embedded human heart tissue using BCA3 antibody. |
| Background: | Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. |
| Synonyms: | Breast cancer-associated gene 3 protein; PKA-interacting protein; AKIP1; |
| UniProt Protein Function: | BCA3: Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. 3 isoforms of the human protein are produced by alternative splicing.Protein type: OncoproteinChromosomal Location of Human Ortholog: 11p15.3Cellular Component: nucleoplasmMolecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q9NQ31 |
| NCBI GenInfo Identifier: | 160358999 |
| NCBI Gene ID: | 56672 |
| NCBI Accession: | Q9NQ31.2 |
| UniProt Secondary Accession: | Q9NQ31,Q8NBS2, Q8TAC6, Q8TAD3, Q8TAE0 |
| UniProt Related Accession: | Q9NQ31 |
| Molecular Weight: | 20,034 Da |
| NCBI Full Name: | A-kinase-interacting protein 1 |
| NCBI Synonym Full Names: | A-kinase interacting protein 1 |
| NCBI Official Symbol: | AKIP1 |
| NCBI Official Synonym Symbols: | BCA3; C11orf17 |
| NCBI Protein Information: | A-kinase-interacting protein 1 |
| UniProt Protein Name: | A-kinase-interacting protein 1 |
| UniProt Synonym Protein Names: | Breast cancer-associated gene 3 protein; PKA-interacting protein; Proline-rich protein BCA3 |
| Protein Family: | A-kinase-interacting protein |
| UniProt Gene Name: | AKIP1 |
| UniProt Entry Name: | AKIP1_HUMAN |
| Antibodies |
| AKIP1 Antibody (PACO00458) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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