AKAP7 Antibody (PACO07668)
- SKU:
- PACO07668
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | AKAP7 Antibody (PACO07668) |
| Antibody SKU: | PACO07668 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human AKAP7 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | A kinase (PRKA) anchor protein 7;AKAP7;AKAP18 ; |
| UniProt Protein Function: | AKAP7 iso1: Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane- associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 6q23 Cellular Component: apical plasma membrane; plasma membrane; cytosol; nucleus; lateral plasma membrane Molecular Function:protein binding; protein kinase A binding; nucleotide binding; protein kinase binding Biological Process: regulation of action potential; protein localization; ion transport |
| NCBI Summary: | This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Apr 2011] |
| UniProt Code: | Q9P0M2 |
| NCBI GenInfo Identifier: | 4757738 |
| NCBI Gene ID: | 9465 |
| NCBI Accession: | NP_004833.1 |
| UniProt Secondary Accession: | Q9P0M2,Q9P0M2, |
| UniProt Related Accession: | O43687,Q9P0M2 |
| Molecular Weight: | 14kDa |
| NCBI Full Name: | A-kinase anchoring protein 7 isoform alpha |
| NCBI Synonym Full Names: | A-kinase anchoring protein 7 |
| NCBI Official Symbol: | AKAP7 |
| NCBI Official Synonym Symbols: | AKAP15; AKAP18 |
| NCBI Protein Information: | A-kinase anchoring protein 7 |
| UniProt Protein Name: | A-kinase anchor protein 7 isoforms alpha and beta |
| UniProt Synonym Protein Names: | A-kinase anchor protein 18 kDa; AKAP 18; Protein kinase A-anchoring protein 7 isoforms alpha/beta; PRKA7 isoforms alpha/beta |
| Protein Family: | A-kinase anchor protein |
| UniProt Gene Name: | AKAP7 |
| UniProt Entry Name: | AKA7A_HUMAN |
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