Description
Product Name: | AKAP10 Polyclonal Antibody |
Product Code: | CAB4493 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:2000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Cellular Location: | Cytoplasm, Membrane, Mitochondrion |
This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 413-662 of human AKAP10 (NP_009133.2). |
Sequence: | DNFQS QLAAK KGQYD GQEAQ NDAMI LYDKY FSLQA THPLG FDDVV RLEIE SNICR EGGPL PNCFT TPLRQ AWTTM EKVFL PGFLS SNLYY KYLND LIHSV RGDEF LGGNV SLTAP GSVGP PDESH PGSSD SSASQ SSVKK ASIKI LKNFD EAIIV DAASL DPESL YQRTY AGKMT FGRVS DLGQF IRESE PEPDV RKSKG SMFSQ AMKKW VQGNT DEAQE ELAWK IAKMI VSDIM QQAQY DQPLE KSTKL |
Synonyms: | PRKA10, AKAP-10, D-AKAP2, D-AKAP-2 |
Calculated MW: | 74kDa |
Observed MW: | Refer to figures |