AKAP1 Polyclonal Antibody
- SKU:
- CAB5943
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
- Applications:
- IP
- Applications:
- FC
Description
| Product Name: | AKAP1 Polyclonal Antibody |
| Product Code: | CAB5943 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunofluorescence, Immunoprecipitation, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, IF/ICC, IP, FC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence, Immunoprecipitation, Flow Cytometry |
| Recommended Dilution: | WB 1:500-1:2000, IF/ICC 1:50-1:100, IP 1:20-1:50, FC 1:20-1:50 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, PC-3 |
| Cellular Location: | Mitochondrion outer membrane |
| Customer Validation: | WB(293T)IF(Mus musculus) IHC(Mus musculus) |
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-280 of human AKAP1 (NP_003479.1). |
| Sequence: | KGHVS SHDEQ QVEAG AVQLR ADPAI KEPLP VEDVC PKVVS TPPSV TEPPE KELST VSKLP AEPPA LLQTH PPCRR SESSG ILPNT TDMRL RPGTR RDDST KLELA LTGGE AKSIP LECPL SSPKG VLFSS KSAEV CKQDS PFSRV PRKVQ PGYPV VPAEK RSSGE RARET GGAEG TGDAV LGEKV LEEAL LSREH VLELE NSKGP SLASL EGEED KGKSS SSQVV GPVQE EEYVA EKLPS RFIES AHTEL A |
| Synonyms: | AKAP, PRKA1, AKAP84, TDRD17, AKAP121, AKAP149, D-AKAP1, PPP1R43, SAKAP84 |
| Calculated MW: | 97kDa |
| Observed MW: | 135kDa |
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