Description
Product Name: | Ajuba Polyclonal Antibody |
Product Code: | CAB21760 |
Reactivity: | Human, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | HepG2, Rat kidney |
Cellular Location: | adherens junction, cell-cell junction, cytosol, Golgi apparatus, microtubule organizing center, nucleoplasm, nucleus, P-body, plasma membrane |
Enables alpha-catenin binding activity and transcription corepressor activity. Involved in several processes, including negative regulation of hippo signaling; positive regulation of gene silencing by miRNA; and regulation of cellular response to hypoxia. Acts upstream of or within gene silencing by miRNA and positive regulation of protein-containing complex assembly. Located in several cellular components, including Golgi apparatus; P-body; and nucleoplasm.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 201-290 of human Ajuba (NP_116265.1). |
Sequence: | PSAYP ELHAA LDRLY AQRPA GFGCQ ESRHS YPPAL GSPGA LAGAG VGAAG PLERR GAQPG RHSVT GYGDC AVGAR YQDEL TALLR LTVGT |
Synonyms: | JUB |
Calculated MW: | 57kDa |
Observed MW: | 55kDa |