AGBL4 Antibody (PACO22298)
- SKU:
- PACO22298
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | AGBL4 Antibody (PACO22298) |
| Antibody SKU: | PACO22298 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from internal of human CBCP6. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HeLa cells, Jurkat cells and A549 cells, using CBCP6 antibody. |
| Background: | Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5 By similarity. |
| Synonyms: | ATP/GTP-binding protein-like 4; CBPC6; CCP6; cytosolic carboxypeptidase 6; EC 3.4.17.- |
| UniProt Protein Function: | Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes polyglutamates from the carboxy-terminus of target proteins such as MYLK. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q5VU57 |
| NCBI GenInfo Identifier: | 119627252 |
| NCBI Gene ID: | 84871 |
| NCBI Accession: | EAX06847.1 |
| UniProt Secondary Accession: | Q5VU57,B3KT26, B4DG37 |
| UniProt Related Accession: | Q5VU57 |
| Molecular Weight: | |
| NCBI Full Name: | ATP/GTP binding protein-like 4 |
| NCBI Synonym Full Names: | ATP/GTP binding protein like 4 |
| NCBI Official Symbol: | AGBL4 |
| NCBI Official Synonym Symbols: | CCP6 |
| NCBI Protein Information: | cytosolic carboxypeptidase 6 |
| UniProt Protein Name: | Cytosolic carboxypeptidase 6 |
| UniProt Synonym Protein Names: | ATP/GTP-binding protein-like 4 |
| Protein Family: | |
| UniProt Gene Name: | AGBL4 |
| UniProt Entry Name: |
| Antibodies |
| AGBL4 Antibody (PACO00375) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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