AGBL3 Antibody (PACO15344)
- SKU:
- PACO15344
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | AGBL3 Antibody (PACO15344) |
| Antibody SKU: | PACO15344 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human AGBL3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15344(AGBL3 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | CCP3 (cytosolic carboxypeptidase 3), also known as AGBL3 (ATP/GTP-binding protein-like 3), is a 1,001 amino acid, cytosolic protein that exists as four alternatively spliced isoforms and belongs to the peptidase M14 family. As a metallocarboxypeptidase, CCP3 binds one zinc ion per subunit and may play a role in the processing of tubulin. The gene that encodes CCP3 consists of approximately 161,457 bases and maps to human chromosome 7q33. Housing over 1,000 genes, chromosome 7 comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. |
| Synonyms: | ATP/GTP binding protein-like 3 |
| UniProt Protein Function: | AGBL3: Metallocarboxypeptidase that may play a role in the processing of tubulin. Belongs to the peptidase M14 family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Protease; EC 3.4.17.-Chromosomal Location of Human Ortholog: 7q33Cellular Component: cytosolMolecular Function: zinc ion binding; metallocarboxypeptidase activityBiological Process: proteolysis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8NEM8 |
| NCBI GenInfo Identifier: | 222352158 |
| NCBI Gene ID: | 340351 |
| NCBI Accession: | NP_848658.3 |
| UniProt Secondary Accession: | Q8NEM8,Q8CDP0 |
| UniProt Related Accession: | Q8NEM8 |
| Molecular Weight: | 116,011 Da |
| NCBI Full Name: | cytosolic carboxypeptidase 3 |
| NCBI Synonym Full Names: | ATP/GTP binding protein-like 3 |
| NCBI Official Symbol: | AGBL3 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | cytosolic carboxypeptidase 3; ATP/GTP-binding protein-like 3 |
| UniProt Protein Name: | Cytosolic carboxypeptidase 3 |
| UniProt Synonym Protein Names: | ATP/GTP-binding protein-like 3 |
| Protein Family: | |
| UniProt Gene Name: | AGBL3 |
| UniProt Entry Name: | CBPC3_HUMAN |
| Antibodies |
| AGBL3 Antibody (PACO04099) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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