AGAP1 Antibody (PACO18527)
- SKU:
- PACO18527
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | AGAP1 Antibody (PACO18527) |
| Antibody SKU: | PACO18527 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human AGAP1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO18527(AGAP1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human liver cancer tissue, hela cells, mouse lung tissue, Primary antibody: PACO18527(AGAP1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18527(AGAP1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system. |
| Synonyms: | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
| UniProt Protein Function: | GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q9UPQ3 |
| NCBI GenInfo Identifier: | 80978930 |
| NCBI Gene ID: | 116987 |
| NCBI Accession: | NP_001032208 |
| UniProt Secondary Accession: | Q9UPQ3,Q541S5, Q6P9D7, Q9NV93, B2RTX7 |
| UniProt Related Accession: | Q9UPQ3 |
| Molecular Weight: | 94/89kd |
| NCBI Full Name: | arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform 1 |
| NCBI Synonym Full Names: | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
| NCBI Official Symbol: | AGAP1 |
| NCBI Official Synonym Symbols: | GGAP1; AGAP-1; CENTG2; cnt-g2 |
| NCBI Protein Information: | arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 |
| UniProt Protein Name: | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 |
| UniProt Synonym Protein Names: | Centaurin-gamma-2; Cnt-g2; GTP-binding and GTPase-activating protein 1; GGAP1 |
| Protein Family: | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein |
| UniProt Gene Name: | AGAP1 |
| UniProt Entry Name: | AGAP1_HUMAN |
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