Description
| Antibody Name: | AF/LE Purified Mouse CD38 Monoclonal Antibody |
| Antibody Code: | AGEL2009 |
| Size: | 500µg |
| Clone: | NIMR5 |
| Synonyms: | ADP-ribosyl cyclase 1,ADPRC 1,CD38,NIM-R5 antigen,2'-phospho-cyclic-ADP-ribose transferase |
| Host Species: | Rat |
| Species Reactivity: | Mouse |
| Applications: | Activ, Stim, FC, ELISA, IHC, IF |
| Concentration: | 1mg/mL |
| Isotype: | IgG2a,k |
| Conjugation: | Azide Free/Low endotoxin |
| Applications: | Activ, Stim, FC, ELISA, IHC, IF |
| Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Storage Buffer: | 0.2 µm filtered in PBS, pH7.2. Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg (< 0.002EU/µg) as Determined by LAL gel clotting assay. Purity is > 95% as determined by SDS-PAGE |
| Storage: | Store at 2-8°C. Do not freeze. |
| Gene ID: | 12494 |
| Uniprot: | P56528 |
| Background: | CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38. |