Description
| Antibody Name: | AF/LE Purified Human IFN-γ Monoclonal Antibody |
| Antibody Code: | AGEL2023 |
| Size: | 500µg |
| Clone: | B27 |
| Synonyms: | Interferon gamma,IFNG,IFN-gamma,IFNγ |
| Host Species: | Mouse |
| Species Reactivity: | Human |
| Applications: | FC, WB, IHC, IP |
| Concentration: | 1mg/mL |
| Isotype: | IgG2a,k |
| Conjugation: | Azide Free/Low endotoxin |
| Applications: | FC, WB, IHC, IP |
| Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Storage Buffer: | 0.2 µm filtered in PBS, pH7.2. Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg (< 0.002EU/µg) as Determined by LAL gel clotting assay. Purity is > 95% as determined by SDS-PAGE |
| Storage: | Store at 2-8°C. Do not freeze. |
| Gene ID: | 3458 |
| Uniprot: | P01579 |
| Background: | Interferon-γ is a potent multifunctional cytokine which is secreted primarily by activated NK cells and T cells. Originally characterized based on anti-viral activities, IFN-γ also exerts anti-proliferative, immunoregulatory, and proinflammatory activities. IFN-γ can upregulate MHC class I and II antigen expression by antigen-presenting cells. The B27 antibody reacts with the human interferon-γ. The B27 antibody can neutralize the bioactivity of natural or recombinant IFN-γ. |