Name: AF/LE Purified Human CD279/PD-1 Monoclonal Antibody [J110](AGEL2093)
SKU: AGEL2093
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AF/LE Purified Human CD279/PD-1 Monoclonal Antibody [J110](AGEL2093)

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SKU:

AGEL2093

Product Type:

Antibody

Antibody Type:

Monoclonal Antibody

Reactivity:

Human

Applications:

Description

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OverviewProduct Name:Purified Anti-Human CD279/PD-1 Antibody [J110]Product Code:AGEL2401Clone No:J110Synonyms:PDCD1,PD1,Protein P

OverviewAntibody Name:AF/LE Purified Human CD44 Monoclonal AntibodyAntibody Code:AGEL2101Size:500µgClone:J110Syn

OverviewAntibody Name:Purified Human CD279/PD-1 Monoclonal AntibodyAntibody Code:AGEL1607Size:100µgClone:J116Syn

OverviewAntibody Name:AF/LE Purified Human CD279/PD-1 Monoclonal AntibodyAntibody Code:AGEL1606Size:500µgClone:J116<

OverviewProduct Name:PD-1/CD279 Monoclonal AntibodyProduct Code:CAB23007Reactivity:Human, Mouse, RatApplications:Western blotting

Concentration:	1mg/mL
Isotype:	IgG2a,k
Conjugation:	Azide Free/Low endotoxin
Applications:	FC
Recommended Dilution:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:	0.2 µm filtered in PBS, pH7.2. Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg (< 0.002EU/µg) as Determined by LAL gel clotting assay. Purity is > 95% as determined by SDS-PAGE
Storage:	Store at 2-8°C. Do not freeze.

Gene ID:	3683
Uniprot:	P20701
Background:	Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.

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Antibody Name:	AF/LE Purified Human CD279/PD-1 Monoclonal Antibody
Antibody Code:	AGEL2093
Size:	500µg
Clone:	J110
Synonyms:	PDCD1,PD1,Protein PD-1,hPD-1
Host Species:	Mouse
Species Reactivity:	Human
Applications:	FC