AF/LE Purified Anti-Mouse CD210 Antibody [1B1.3A]
- SKU:
- AGEL2166
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Applications:
- Block
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- Rat IgG1, κ
- Clone:
- 1B1.3A
- Conjugation:
- None (Low endotoxin)
Description
Product Name: | AF/LE Purified Anti-Mouse CD210 Antibody [1B1.3A] |
Product Code: | AGEL2166 |
Clone No: | 1B1.3A |
Synonyms: | Interleukin-10 receptor subunit alpha,Il10ra,IL-10 receptor subunit alpha, IL-10R subunit alpha,IL-10RA,CDw210a,Interleukin-10 receptor subunit 1,IL-10R subunit 1,IL-10R1,CD210,Il10ra |
Reactivity: | Mouse |
Host Species: | Rat |
Applications: | FCM, Block |
Isotype: | Rat IgG1, κ |
Isotype Control: | Low Endotoxin Purified Rat IgG1, κ Isotype Control [HRPN] (AGEL2628) |
Conjugation: | None (Purified antibody-Azide Free/Low endotoxin) |
Form: | Liquid |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
Swissprot: | Q61727 |
Stability & Storage: | Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Shipping: | Biological ice pack at 4°C |
CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210 induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulation results in the inhibition of cytokine production and the costimulation of B cell proliferation and differentiation. The only known ligand for this receptor is IL-10.