AF/LE Purified Anti-Mouse CD209b Antibody [22D1]
- SKU:
- AGEL2158
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Mouse
- Host Species:
- Armenian Hamster
- Isotype:
- Armenian Hamster IgG
- Clone:
- 22D1
- Conjugation:
- None (Low endotoxin)
Description
| Product Name: | AF/LE Purified Anti-Mouse CD209b Antibody [22D1] |
| Product Code: | AGEL2158 |
| Clone No: | 22D1 |
| Synonyms: | CD209 antigen-like protein B,Cd209b,DC-SIGN-related protein 1,DC-SIGNR1,OtB7,CD209,Cd209b |
| Reactivity: | Mouse |
| Host Species: | Armenian Hamster |
| Applications: | FCM |
| Isotype: | Armenian Hamster IgG |
| Isotype Control: | Low Endotoxin Purified Armenian Hamster IgG Isotype Control [PIP] (AGEL2697) |
| Conjugation: | None (Purified antibody-Azide Free/Low endotoxin) |
| Form: | Liquid |
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Storage Buffer: | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| Swissprot: | Q8CJ91 |
| Stability & Storage: | Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.
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