AF/LE Purified Anti-Mouse CD106 Antibody [M/K-2.7]

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SKU:
AGEL2178

Description

Product Name:AF/LE Purified Anti-Mouse CD106 Antibody [M/K-2.7]
Product Code:AGEL2178
Clone No:M/K-2.7
Synonyms:Vascular cell adhesion protein 1,Vcam1,V-CAM 1,VCAM-1,CD106
Reactivity:Mouse
Host Species:Rat
Applications:FCM
Isotype:Rat IgG1, κ
Isotype Control:Low Endotoxin Purified Rat IgG1, κ Isotype Control [HRPN] (AGEL2628)
Conjugation:None (Purified antibody-Azide Free/Low endotoxin)
Form:Liquid
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Swissprot:P29533
Stability & Storage:Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C

CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).

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Additional Information

Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG1, κ
Clone:
M/K-2.7
Conjugation:
None (Low endotoxin)
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