ADPRHL2 Antibody (PACO19150)
- SKU:
- PACO19150
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ADPRHL2 Antibody (PACO19150) |
| Antibody SKU: | PACO19150 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human ADPRHL2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela cells, mouse kidney tissue, Primary antibody: PACO19150(ADPRHL2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
| Background: | This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm. Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-(ADP-ribose), but does not hydrolyze ADP-ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Due to catalytic inactivity of PARG mitochondrial isoforms, ARH3 is the only PAR hydrolyzing enzyme in mitochondria. |
| Synonyms: | ADP-ribosylhydrolase like 2 |
| UniProt Protein Function: | ADPRHL2: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribose from poly-(ADP-ribose), but does not hydrolyze ADP- ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Belongs to the ADP-ribosylglycohydrolase family.Protein type: Hydrolase; EC 3.2.1.143Chromosomal Location of Human Ortholog: 1p34.3Cellular Component: nucleoplasm |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the ADP-ribosylglycohydrolase family. The encoded enzyme catalyzes the removal of ADP-ribose from ADP-ribosylated proteins. This enzyme localizes to the mitochondria, in addition to the nucleus and cytoplasm.[provided by RefSeq, Feb 2009] |
| UniProt Code: | Q9NX46 |
| NCBI GenInfo Identifier: | 74753038 |
| NCBI Gene ID: | 54936 |
| NCBI Accession: | Q9NX46.1 |
| UniProt Secondary Accession: | Q9NX46,Q53G94, Q6IAB8, Q9BY47 |
| UniProt Related Accession: | Q9NX46 |
| Molecular Weight: | 38,947 Da |
| NCBI Full Name: | Poly(ADP-ribose) glycohydrolase ARH3 |
| NCBI Synonym Full Names: | ADP-ribosylhydrolase like 2 |
| NCBI Official Symbol: | ADPRHL2 |
| NCBI Official Synonym Symbols: | ARH3 |
| NCBI Protein Information: | poly(ADP-ribose) glycohydrolase ARH3 |
| UniProt Protein Name: | Poly(ADP-ribose) glycohydrolase ARH3 |
| UniProt Synonym Protein Names: | ADP-ribosylhydrolase 3; [Protein ADP-ribosylarginine] hydrolase-like protein 2 |
| Protein Family: | Poly(ADP-ribose) glycohydrolase |
| UniProt Gene Name: | ADPRHL2 |
| UniProt Entry Name: | ARHL2_HUMAN |
| Antibodies |
| ADPRHL2 Antibody (PACO07625) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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