ADO Antibody (PACO58340)
- SKU:
- PACO58340
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ADO Antibody (PACO58340) |
| Antibody SKU: | PACO58340 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human 2-aminoethanethiol dioxygenase protein (137-270AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO58340 diluted at 1:400 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | cytosol, mitochondrion, cysteamine dioxygenase activity, oxidation-reduction process, sulfur amino acid, catabolic process |
| Synonyms: | 2-aminoethanethiol dioxygenase (EC 1.13.11.19) (Cysteamine dioxygenase), ADO, C10orf22 |
| UniProt Protein Function: | ADO: |
| UniProt Protein Details: | Protein type:EC 1.13.11.19; Oxidoreductase; Other Amino Acids Metabolism - taurine and hypotaurine Chromosomal Location of Human Ortholog: 10q21.3 Cellular Component: mitochondrion Molecular Function:metal ion binding; cysteamine dioxygenase activity |
| NCBI Summary: | Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine (Dominy et al., 2007 [PubMed 17581819]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q96SZ5 |
| NCBI GenInfo Identifier: | 88984104 |
| NCBI Gene ID: | 84890 |
| NCBI Accession: | Q96SZ5.2 |
| UniProt Related Accession: | Q96SZ5 |
| Molecular Weight: | 30kDa |
| NCBI Full Name: | 2-aminoethanethiol dioxygenase |
| NCBI Synonym Full Names: | 2-aminoethanethiol dioxygenase |
| NCBI Official Symbol: | ADO |
| NCBI Official Synonym Symbols: | C10orf22 |
| NCBI Protein Information: | 2-aminoethanethiol dioxygenase |
| UniProt Protein Name: | 2-aminoethanethiol dioxygenase |
| UniProt Synonym Protein Names: | Cysteamine dioxygenase |
| Protein Family: | AdoMet-dependent rRNA methyltransferase |
| UniProt Gene Name: | ADO |
| UniProt Entry Name: | AEDO_HUMAN |
| Antibodies |
| ADO Antibody (PACO07622) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
