Description
| Antibody Name: | ADO Antibody (PACO17494) |
| Antibody SKU: | PACO17494 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human ADO |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: PACO17494(ADO Antibody) at dilution 1/300 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 5 minutes. |
| Background: | Human thiol dioxygenases include cysteine dioxygenase (CDO, MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO, EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine. |
| Synonyms: | 2-aminoethanethiol dioxygenase |
| UniProt Protein Function: | ADO: |
| UniProt Protein Details: | Protein type:EC 1.13.11.19; Oxidoreductase; Other Amino Acids Metabolism - taurine and hypotaurine Chromosomal Location of Human Ortholog: 10q21.3 Cellular Component: mitochondrion Molecular Function:metal ion binding; cysteamine dioxygenase activity |
| NCBI Summary: | Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine (Dominy et al., 2007 [PubMed 17581819]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q96SZ5 |
| NCBI GenInfo Identifier: | 88984104 |
| NCBI Gene ID: | 84890 |
| NCBI Accession: | Q96SZ5.2 |
| UniProt Related Accession: | Q96SZ5 |
| Molecular Weight: | 30kDa |
| NCBI Full Name: | 2-aminoethanethiol dioxygenase |
| NCBI Synonym Full Names: | 2-aminoethanethiol dioxygenase |
| NCBI Official Symbol: | ADO |
| NCBI Official Synonym Symbols: | C10orf22 |
| NCBI Protein Information: | 2-aminoethanethiol dioxygenase |
| UniProt Protein Name: | 2-aminoethanethiol dioxygenase |
| UniProt Synonym Protein Names: | Cysteamine dioxygenase |
| Protein Family: | AdoMet-dependent rRNA methyltransferase |
| UniProt Gene Name: | ADO |
| UniProt Entry Name: | AEDO_HUMAN |
| Antibodies |
| ADO Antibody (PACO07622) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
