Antibody Name:	ADIPOQ Antibody (PACO35942)
Antibody SKU:	PACO35942
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:	Bovine
Immunogen:	Recombinant Bovine Adiponectin protein (18-240AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Western blot. All lanes: ADIPOQ antibody at 2µg/ml + Recombinant Adiponectin protein 0.1µg. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 27 kDa. Observed band size: 27 kDa.

Background:

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid, combustion. Antagonizes TNF-α by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

Synonyms:

Adiponectin (30 kDa adipocyte complement-related protein) (Adipocyte complement-related 30 kDa protein) (ACRP30) (Adipocyte, C1q and collagen domain-containing protein) (Adipose most abundant gene transcript 1 protein) (apM-1), ADIPOQ, ACRP30 APM1

UniProt Protein Function:	Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW ().
UniProt Protein Details:
NCBI Summary:
UniProt Code:	Q3Y5Z3
NCBI GenInfo Identifier:	27807433
NCBI Gene ID:	282865
NCBI Accession:	NP_777167.1
UniProt Secondary Accession:	Q3Y5Z3,Q95MQ4, A5D7A8
UniProt Related Accession:	Q3Y5Z3
Molecular Weight:	26,133 Da
NCBI Full Name:	adiponectin
NCBI Synonym Full Names:	adiponectin, C1Q and collagen domain containing
NCBI Official Symbol:	ADIPOQ
NCBI Official Synonym Symbols:	APM1; ACRP30
NCBI Protein Information:	adiponectin
UniProt Protein Name:	Adiponectin
UniProt Synonym Protein Names:	30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; ACRP30; Adipocyte, C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1 protein; apM-1
Protein Family:
UniProt Gene Name:	ADIPOQ
UniProt Entry Name: