ADAT1 Antibody (PACO40486)
- SKU:
- PACO40486
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ADAT1 Antibody (PACO40486) |
| Antibody SKU: | PACO40486 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human tRNA-specific adenosine deaminase 1 protein (1-501AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: ADAT1 antibody at 6µg/ml + MDA-MB-231 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 56, 39 kDa. Observed band size: 56 kDa. |
 | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO40486 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human skin tissue using PACO40486 at dilution of 1:100. |
| Background: | Specifically deaminates adenosine-37 to inosine in tRNA-Ala. |
| Synonyms: | tRNA-specific adenosine deaminase 1 (hADAT1) (EC 3.5.4.34) (tRNA-specific adenosine-37 deaminase), ADAT1 |
| UniProt Protein Function: | ADAT1: Specifically deaminates adenosine-37 to inosine in tRNA- Ala. Belongs to the ADAT1 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: RNA processing; EC 3.5.4.34; HydrolaseChromosomal Location of Human Ortholog: 16q23.1Molecular Function: RNA binding; tRNA-specific adenosine deaminase activityBiological Process: tRNA processing |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the ADAR (adenosine deaminase acting on RNA) family. Using site-specific adenosine modification, proteins encoded by these genes participate in the pre-mRNA editing of nuclear transcripts. The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010] |
| UniProt Code: | Q9BUB4 |
| NCBI GenInfo Identifier: | 74733201 |
| NCBI Gene ID: | 23536 |
| NCBI Accession: | Q9BUB4.1 |
| UniProt Secondary Accession: | Q9BUB4,Q9NVB7, Q9UNG3 |
| UniProt Related Accession: | Q9BUB4 |
| Molecular Weight: | 38,706 Da |
| NCBI Full Name: | tRNA-specific adenosine deaminase 1 |
| NCBI Synonym Full Names: | adenosine deaminase, tRNA specific 1 |
| NCBI Official Symbol: | ADAT1 |
| NCBI Official Synonym Symbols: | HADAT1 |
| NCBI Protein Information: | tRNA-specific adenosine deaminase 1 |
| UniProt Protein Name: | tRNA-specific adenosine deaminase 1 |
| UniProt Synonym Protein Names: | tRNA-specific adenosine-37 deaminase |
| Protein Family: | tRNA-specific adenosine deaminase |
| UniProt Gene Name: | ADAT1 |
| UniProt Entry Name: | ADAT1_HUMAN |
| Antibodies |
| ADAT1 Antibody (PACO07605) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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