Name: ADAMTS6 Antibody (PACO18516)
SKU: PACO18516
Availability: OutOfStock

Antibody Name:	ADAMTS6 Antibody (PACO18516)
Antibody SKU:	PACO18516
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:1000-1:5000, IHC:1:15-1:50
Species Reactivity:	Human
Immunogen:	Synthetic peptide of human ADAMTS6

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18516(ADAMTS6 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.

Synonyms:

ADAM metallopeptidase with thrombospondin type 1 motif, 6

UniProt Protein Function:	ADAMTS6: a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. [provided by RefSeq, Jul 2008]
UniProt Protein Details:	Protein type:EC 3.4.24.-; Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted; Protease Chromosomal Location of Human Ortholog: 5q12 Molecular Function:metallopeptidase activity
NCBI Summary:	This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Expression of this gene may be regulated by the cytokine TNF-alpha. [provided by RefSeq, Mar 2016]
UniProt Code:	Q9UKP5
NCBI GenInfo Identifier:	229462816
NCBI Gene ID:	11174
NCBI Accession:	Q9UKP5.2
UniProt Secondary Accession:	Q9UKP5,Q59EX6, Q5IR87, Q5IR88, Q5IR89, Q68DL1,
UniProt Related Accession:	Q9UKP5
Molecular Weight:	34,189 Da
NCBI Full Name:	A disintegrin and metalloproteinase with thrombospondin motifs 6
NCBI Synonym Full Names:	ADAM metallopeptidase with thrombospondin type 1 motif 6
NCBI Official Symbol:	ADAMTS6
NCBI Official Synonym Symbols:	ADAM-TS6; ADAMTS-6; ADAM-TS 6
NCBI Protein Information:	A disintegrin and metalloproteinase with thrombospondin motifs 6
UniProt Protein Name:	A disintegrin and metalloproteinase with thrombospondin motifs 6
Protein Family:	A disintegrin and metalloproteinase with thrombospondin motifs
UniProt Gene Name:	ADAMTS6
UniProt Entry Name:	ATS6_HUMAN