ADAMTS10 Antibody (PACO19055)
- SKU:
- PACO19055
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ADAMTS10 Antibody (PACO19055) |
| Antibody SKU: | PACO19055 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human ADAMTS10 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO19055(ADAMTS10 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19055(ADAMTS10 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. |
| Synonyms: | ADAM metallopeptidase with thrombospondin type 1 motif, 10 |
| UniProt Protein Function: | Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9H324 |
| NCBI GenInfo Identifier: | 537544568 |
| NCBI Gene ID: | 81794 |
| NCBI Accession: | NP_001269281.1 |
| UniProt Secondary Accession: | Q9H324,M0QZE4 |
| UniProt Related Accession: | Q9H324 |
| Molecular Weight: | 121 |
| NCBI Full Name: | A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform 2 |
| NCBI Synonym Full Names: | ADAM metallopeptidase with thrombospondin type 1 motif 10 |
| NCBI Official Symbol: | ADAMTS10 |
| NCBI Official Synonym Symbols: | WMS; WMS1; ADAM-TS10; ADAMTS-10 |
| NCBI Protein Information: | A disintegrin and metalloproteinase with thrombospondin motifs 10 |
| UniProt Protein Name: | A disintegrin and metalloproteinase with thrombospondin motifs 10 |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | ADAMTS10 |
| UniProt Entry Name: |
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