ADAMTS1 Monoclonal Antibody
- SKU:
- CAB23840
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IF
Description
| Product Name: | ADAMTS1 Monoclonal Antibody |
| Product Code: | CAB23840 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC61847 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | IF/ICC, ELISA |
| Key Applications: | Immunofluorescence |
| Recommended Dilution: | IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Secreted, extracellular matrix, extracellular space |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
| Immunogen: | Recombinant fusion protein containing a sequen cecorresponding to amino acids 50-174 of human ADAMTS1(NP_008919.3). |
| Sequence: | LGRPS EEDEE LVVPE LERAP GHGTT RLRLH AFDQQ LDLEL RPDSS FLAPG FTLQN VGRKS GSETP LPETD LAHCF YSGTV NGDPS SAAAL SLCEG VRGAF YLLGE AYFIQ PLPAA SERLA TAAPG |
| Synonyms: | ADAMTS1, C3-C5, METH1, ADAM metallopeptidase with thrombospondin type 1 motif 1 |
| Calculated MW: | 105kDa |
| Observed MW: | Refer to figures |
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