ADAM21 Antibody (PACO15312)
- SKU:
- PACO15312
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ADAM21 Antibody (PACO15312) |
| Antibody SKU: | PACO15312 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:15-1:50 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human ADAM21 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO15312(ADAM21 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15312(ADAM21 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The expression of this gene expression is testis-specific. |
| Synonyms: | ADAM metallopeptidase domain 21 |
| UniProt Protein Function: | ADAM21: May be involved in sperm maturation and/or fertilization. May also be involved in epithelia functions associated with establishing and maintaining gradients of ions or nutrients.Protein type: EC 3.4.24.-; Protease; Motility/polarity/chemotaxis; Membrane protein, integralChromosomal Location of Human Ortholog: 14q24.1Cellular Component: plasma membraneMolecular Function: metallopeptidase activityBiological Process: binding of sperm to zona pellucida; single fertilization |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The expression of this gene expression is testis-specific. [provided by RefSeq, May 2011] |
| UniProt Code: | Q9UKJ8 |
| NCBI GenInfo Identifier: | 296434388 |
| NCBI Gene ID: | 8747 |
| NCBI Accession: | Q9UKJ8.2 |
| UniProt Secondary Accession: | Q9UKJ8,O43507, Q2VPC6, Q32MR0 |
| UniProt Related Accession: | Q9UKJ8 |
| Molecular Weight: | 80,834 Da |
| NCBI Full Name: | Disintegrin and metalloproteinase domain-containing protein 21 |
| NCBI Synonym Full Names: | ADAM metallopeptidase domain 21 |
| NCBI Official Symbol: | ADAM21 |
| NCBI Official Synonym Symbols: | ADAM31; ADAM 21 |
| NCBI Protein Information: | disintegrin and metalloproteinase domain-containing protein 21 |
| UniProt Protein Name: | Disintegrin and metalloproteinase domain-containing protein 21 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Disintegrin and metalloproteinase domain-containing protein |
| UniProt Gene Name: | ADAM21 |
| UniProt Entry Name: | ADA21_HUMAN |
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