Description
Product Name: | ACTR1B Monoclonal Antibody |
Product Code: | CAB21140 |
Reactivity: | Human, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC3033 |
Reactivity: | Human, Rat |
Tested Applications: | WB, IHC-P, IP, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200, IP 1:1000-1:5000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | HeLa, Hep G2, Jurkat, U-87MG, Rat brain |
Cellular Location: | Cytoplasm, Centrosome, Cytoskeleton, Microtubule organizing center |
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.
Immunogen: | Recombinant protein of Human ACTR1B. |
Sequence: | Email for sequence |
Synonyms: | PC3, ARP1B, CTRN2 |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |