Activator protein 2 (AP-2/TFAP2A) Polyclonal Antibody

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SKU:
CAB21727
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:Activator protein 2 (AP-2/TFAP2A) Polyclonal Antibody
Product Code:CAB21727
Reactivity:Human, Rat
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:HeLa, C6
Cellular Location:Nucleus

The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Activator protein 2 (AP-2/TFAP2A) (NP_003211.1).
Sequence:RQSQE SGLLH THRGL PHQLS GLDPR RDYRR HEDLL HGPHA LSSGL GDLSI HSLPH AIEEV PHVED PGINI PDQTV IKKGP VSLSK SNSNA VSAIP INKDN L
Synonyms:AP-2, BOFS, AP2TF, TFAP2, AP-2alpha
Calculated MW:48kDa
Observed MW:50kDa
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