Activator protein 2 (AP-2/TFAP2A) Polyclonal Antibody
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- SKU:
- CAB21727
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Activator protein 2 (AP-2/TFAP2A) Polyclonal Antibody |
| Product Code: | CAB21727 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, C6 |
| Cellular Location: | Nucleus |
The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Activator protein 2 (AP-2/TFAP2A) (NP_003211.1). |
| Sequence: | RQSQE SGLLH THRGL PHQLS GLDPR RDYRR HEDLL HGPHA LSSGL GDLSI HSLPH AIEEV PHVED PGINI PDQTV IKKGP VSLSK SNSNA VSAIP INKDN L |
| Synonyms: | AP-2, BOFS, AP2TF, TFAP2, AP-2alpha |
| Calculated MW: | 48kDa |
| Observed MW: | 50kDa |
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