ACSL3 Monoclonal Antibody
- SKU:
- CAB22085
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | ACSL3 Monoclonal Antibody |
| Product Code: | CAB22085 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55219 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:10000-1:30000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | K-562, HeLa, Mouse spinal cord, Rat brain |
| Cellular Location: | Endoplasmic reticulum membrane, Microsome membrane, Mitochondrion outer membrane, Peroxisome membrane, Single-pass type III membrane protein |
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600-700 of human ACSL3 (NP_004448.2). |
| Sequence: | ALKNL PLVDN ICAYA NSYHS YVIGF VVPNQ KELTE LARKK GLKGT WEELC NSCEM ENEVL KVLSE AAISA SLEKF EIPVK IRLSP EPWTP ETGLV TDAFK L |
| Synonyms: | ACS3, FACL3, LACS3, LACS 3, PRO2194 |
| Calculated MW: | 80kDa |
| Observed MW: | 75kDa |
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