ACSBG2 Antibody (PACO36122)
- SKU:
- PACO36122
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ACSBG2 Antibody (PACO36122) |
| Antibody SKU: | PACO36122 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Long-chain-fatty-acid, -CoA ligase ACSBG2 protein (301-600AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: ACSBG2 antibody at 4µg/ml. Lane 1: A431 whole cell lysate. Lane 2: K562 whole cell lysate. Lane 3: A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 75, 69, 54, 52 kDa. Observed band size: 52 kDa. |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO36122 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO36122 at dilution of 1:100. |
| Background: | Mediates activation of long-chain fatty acid, for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acid,. Also able to activate very long-chain fatty acid, ; however, the relevance of such activity is unclear in vivo. Has increased ability to activate oleic and linoleic acid, May play a role in spermatogenesis. |
| Synonyms: | Long-chain-fatty-acid, -CoA ligase ACSBG2 (EC 6.2.1.3) (Acyl-CoA synthetase bubblegum family member 2) (Bubblegum-related protein) (PRTD-NY3), ACSBG2, BGR |
| UniProt Protein Function: | ACSBG2: Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Has increased ability to activate oleic and linoleic acid. May play a role in spermatogenesis. Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Mitochondrial; Hydrolase; Ligase; EC 6.2.1.3Chromosomal Location of Human Ortholog: 19p13.3Cellular Component: cytoplasm; cytosol; mitochondrionMolecular Function: acyl-CoA hydrolase activity; long-chain-fatty-acid-CoA ligase activity; very-long-chain-fatty-acid-CoA ligase activityBiological Process: fatty acid metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q5FVE4 |
| NCBI GenInfo Identifier: | 296434386 |
| NCBI Gene ID: | 81616 |
| NCBI Accession: | Q5FVE4.2 |
| UniProt Secondary Accession: | Q5FVE4,Q6UWJ3, Q7Z5A0, Q8WW03, Q96M36, Q9BYZ3, Q9H0C4 B3KSF2 |
| UniProt Related Accession: | Q5FVE4 |
| Molecular Weight: | 51,891 Da |
| NCBI Full Name: | Long-chain-fatty-acid--CoA ligase ACSBG2 |
| NCBI Synonym Full Names: | acyl-CoA synthetase bubblegum family member 2 |
| NCBI Official Symbol: | ACSBG2 |
| NCBI Official Synonym Symbols: | BGR; BRGL; PRTDNY3; PRTD-NY3 |
| NCBI Protein Information: | long-chain-fatty-acid--CoA ligase ACSBG2 |
| UniProt Protein Name: | Long-chain-fatty-acid--CoA ligase ACSBG2 |
| UniProt Synonym Protein Names: | Acyl-CoA synthetase bubblegum family member 2; Bubblegum-related protein; PRTD-NY3 |
| Protein Family: | Long-chain-fatty-acid--CoA ligase |
| UniProt Gene Name: | ACSBG2 |
| UniProt Entry Name: | ACBG2_HUMAN |
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