ACPT Antibody (PACO18647)
- SKU:
- PACO18647
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ACPT Antibody (PACO18647) |
| Antibody SKU: | PACO18647 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human ACPT |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18647(ACPT Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO18647(ACPT Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | acid, phosphatases are enzymes capable of hydrolyzing orthophosphoric acid, esters in an acid, medium. This gene is up-regulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. This gene exhibits a lower level of expression in testicular cancer tissues than in normal tissues. The protein encoded by this gene has structural similarity to prostatic and lysosomal acid, phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. |
| Synonyms: | acid, phosphatase, testicular |
| UniProt Protein Function: | ACPT: Dephosphorylates receptor tyrosine-protein kinase erbB-4 and inhibits the ligand-induced proteolytic cleavage. Belongs to the histidine acid phosphatase family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Cofactor and Vitamin Metabolism - riboflavin; Phosphatase (non-protein); Membrane protein, integral; EC 3.1.3.2; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 19q13.4Cellular Component: integral to membraneMolecular Function: acid phosphatase activityBiological Process: dephosphorylation |
| UniProt Protein Details: | |
| NCBI Summary: | Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is up-regulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. This gene exhibits a lower level of expression in testicular cancer tissues than in normal tissues. The protein encoded by this gene has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BZG2 |
| NCBI GenInfo Identifier: | 12958660 |
| NCBI Gene ID: | 93650 |
| NCBI Accession: | AAK09393.1 |
| UniProt Secondary Accession: | Q9BZG2,Q9BZG3, Q9BZG4, C0H3P7 |
| UniProt Related Accession: | Q9BZG2 |
| Molecular Weight: | 46,090 Da |
| NCBI Full Name: | acid phosphatase |
| NCBI Synonym Full Names: | acid phosphatase, testicular |
| NCBI Official Symbol: | ACPT |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | testicular acid phosphatase |
| UniProt Protein Name: | Testicular acid phosphatase |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | ACPT |
| UniProt Entry Name: | PPAT_HUMAN |
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