Name: ACOT11 Antibody (PACO40030)
SKU: PACO40030
Availability: OutOfStock

Antibody Name:	ACOT11 Antibody (PACO40030)
Antibody SKU:	PACO40030
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA
Recommended Dilutions:
Species Reactivity:	Human
Immunogen:	Recombinant Human Acyl-coenzyme A thioesterase 11 protein (35-254AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Background:	Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates.
Synonyms:	Acyl-coenzyme A thioesterase 11 (Acyl-CoA thioesterase 11) (EC 3.1.2.-) (Acyl-CoA thioester hydrolase 11) (Adipose-associated thioesterase) (Brown fat-inducible thioesterase) (BFIT), ACOT11, BFIT KIAA0707 THEA

UniProt Protein Function:	ACOT11: Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Hydrolase; EC 3.1.2.-Chromosomal Location of Human Ortholog: 1p32.3Cellular Component: cytoplasmMolecular Function: acyl-CoA hydrolase activity; lipid bindingBiological Process: response to temperature stimulus; response to cold; fatty acid metabolic process
UniProt Protein Details:
NCBI Summary:	This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
UniProt Code:	Q8WXI4
NCBI GenInfo Identifier:	21363000
NCBI Gene ID:	26027
NCBI Accession:	Q8WXI4.1
UniProt Secondary Accession:	Q8WXI4,O75187, Q52LP1, Q53ER9, Q96DI1, Q9H883, B1AQ22 D3DQ50
UniProt Related Accession:	Q8WXI4
Molecular Weight:	67,152 Da
NCBI Full Name:	Acyl-coenzyme A thioesterase 11
NCBI Synonym Full Names:	acyl-CoA thioesterase 11
NCBI Official Symbol:	ACOT11
NCBI Official Synonym Symbols:	BFIT; THEA; THEM1; STARD14
NCBI Protein Information:	acyl-coenzyme A thioesterase 11; START domain containing 14; acyl-CoA thioester hydrolase 11; adipose-associated thioesterase; brown fat-inducible thioesterase; thioesterase, adipose associated; thioesterase superfamily member 1; StAR-related lipid transfer (START) domain containing 14
UniProt Protein Name:	Acyl-coenzyme A thioesterase 11
UniProt Synonym Protein Names:	Acyl-CoA thioester hydrolase 11; Adipose-associated thioesterase; Brown fat-inducible thioesterase; BFIT
Protein Family:	Acyl-coenzyme A thioesterase
UniProt Gene Name:	ACOT11
UniProt Entry Name:	ACO11_HUMAN