Name: ACOT1 Antibody (PACO23373)
SKU: PACO23373
Availability: OutOfStock

Antibody Name:	ACOT1 Antibody (PACO23373)
Antibody SKU:	PACO23373
Size:	100ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:3000, IF:1:100-1:500
Species Reactivity:	Human
Immunogen:	Synthesized peptide derived from internal of human ACOT1.

Form:	Liquid
Storage Buffer:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western blot analysis of extracts from Jurkat cells, using ACOT1 antibody.
	Immunofluorescence analysis of MCF-7 cells, using ACOT1 antibody.

Background:	Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16 By similarity.
Synonyms:	ACH2; CTE-1; EC 3.1.2.2; LACH2;

UniProt Protein Function:	ACOT1: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16. Belongs to the C/M/P thioester hydrolase family.Protein type: EC 3.1.2.2; Hydrolase; Lipid Metabolism - unsaturated fatty acid biosynthesisChromosomal Location of Human Ortholog: 14q24.3Cellular Component: cytosolMolecular Function: acyl-CoA hydrolase activity; palmitoyl-CoA hydrolase activityBiological Process: acyl-CoA metabolic process; very-long-chain fatty acid metabolic process; long-chain fatty acid metabolic process
UniProt Protein Details:
NCBI Summary:
UniProt Code:	Q86TX2
NCBI GenInfo Identifier:	81230485
NCBI Gene ID:	641371
NCBI Accession:	NP_001032238.1
UniProt Secondary Accession:	Q86TX2,Q3I5F9, A1L173
UniProt Related Accession:	Q86TX2
Molecular Weight:	46,277 Da
NCBI Full Name:	acyl-coenzyme A thioesterase 1
NCBI Synonym Full Names:	acyl-CoA thioesterase 1
NCBI Official Symbol:	ACOT1
NCBI Official Synonym Symbols:	ACH2; CTE-1; LACH2
NCBI Protein Information:	acyl-coenzyme A thioesterase 1; CTE-I; CTE-Ib; long chain acyl-CoA hydrolase; long chain acyl-CoA thioester hydrolase; inducible cytosolic acyl-coenzyme A thioester hydrolase
UniProt Protein Name:	Acyl-coenzyme A thioesterase 1
UniProt Synonym Protein Names:	CTE-I; CTE-Ib; Inducible cytosolic acyl-coenzyme A thioester hydrolase; Long chain acyl-CoA thioester hydrolase; Long chain acyl-CoA hydrolase
Protein Family:	Acyl-coenzyme A thioesterase
UniProt Gene Name:	ACOT1
UniProt Entry Name:	ACOT1_HUMAN