ACOT1 Antibody (PACO15260)
- SKU:
- PACO15260
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ACOT1 Antibody (PACO15260) |
| Antibody SKU: | PACO15260 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human ACOT1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO15260(ACOT1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Acyl-CoA thioesterases such as ACOT1, hydrolyze acyl-CoAs to the free fatty acid, and CoA. ACOTs therefore play key roles in maintaining the intracellular ratio between CoA esters of various lipids and free fatty acid, Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid, and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acid, and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16. |
| Synonyms: | acyl-CoA thioesterase 1 |
| UniProt Protein Function: | ACOT1: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16. Belongs to the C/M/P thioester hydrolase family.Protein type: EC 3.1.2.2; Hydrolase; Lipid Metabolism - unsaturated fatty acid biosynthesisChromosomal Location of Human Ortholog: 14q24.3Cellular Component: cytosolMolecular Function: acyl-CoA hydrolase activity; palmitoyl-CoA hydrolase activityBiological Process: acyl-CoA metabolic process; very-long-chain fatty acid metabolic process; long-chain fatty acid metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q86TX2 |
| NCBI GenInfo Identifier: | 81230485 |
| NCBI Gene ID: | 641371 |
| NCBI Accession: | NP_001032238.1 |
| UniProt Secondary Accession: | Q86TX2,Q3I5F9, A1L173 |
| UniProt Related Accession: | Q86TX2 |
| Molecular Weight: | 46,277 Da |
| NCBI Full Name: | acyl-coenzyme A thioesterase 1 |
| NCBI Synonym Full Names: | acyl-CoA thioesterase 1 |
| NCBI Official Symbol: | ACOT1 |
| NCBI Official Synonym Symbols: | ACH2; CTE-1; LACH2 |
| NCBI Protein Information: | acyl-coenzyme A thioesterase 1; CTE-I; CTE-Ib; long chain acyl-CoA hydrolase; long chain acyl-CoA thioester hydrolase; inducible cytosolic acyl-coenzyme A thioester hydrolase |
| UniProt Protein Name: | Acyl-coenzyme A thioesterase 1 |
| UniProt Synonym Protein Names: | CTE-I; CTE-Ib; Inducible cytosolic acyl-coenzyme A thioester hydrolase; Long chain acyl-CoA thioester hydrolase; Long chain acyl-CoA hydrolase |
| Protein Family: | Acyl-coenzyme A thioesterase |
| UniProt Gene Name: | ACOT1 |
| UniProt Entry Name: | ACOT1_HUMAN |
| Antibodies |
| ACOT1 Antibody (PACO05017) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
