| UniProt Protein Function: | ACOT1: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16. Belongs to the C/M/P thioester hydrolase family.Protein type: EC 3.1.2.2; Hydrolase; Lipid Metabolism - unsaturated fatty acid biosynthesisChromosomal Location of Human Ortholog: 14q24.3Cellular Component: cytosolMolecular Function: acyl-CoA hydrolase activity; palmitoyl-CoA hydrolase activityBiological Process: acyl-CoA metabolic process; very-long-chain fatty acid metabolic process; long-chain fatty acid metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q86TX2 |
| NCBI GenInfo Identifier: | 81230485 |
| NCBI Gene ID: | 641371 |
| NCBI Accession: | NP_001032238.1 |
| UniProt Secondary Accession: | Q86TX2,Q3I5F9, A1L173 |
| UniProt Related Accession: | Q86TX2 |
| Molecular Weight: | 46,277 Da |
| NCBI Full Name: | acyl-coenzyme A thioesterase 1 |
| NCBI Synonym Full Names: | acyl-CoA thioesterase 1 |
| NCBI Official Symbol: | ACOT1 |
| NCBI Official Synonym Symbols: | ACH2; CTE-1; LACH2 |
| NCBI Protein Information: | acyl-coenzyme A thioesterase 1; CTE-I; CTE-Ib; long chain acyl-CoA hydrolase; long chain acyl-CoA thioester hydrolase; inducible cytosolic acyl-coenzyme A thioester hydrolase |
| UniProt Protein Name: | Acyl-coenzyme A thioesterase 1 |
| UniProt Synonym Protein Names: | CTE-I; CTE-Ib; Inducible cytosolic acyl-coenzyme A thioester hydrolase; Long chain acyl-CoA thioester hydrolase; Long chain acyl-CoA hydrolase |
| Protein Family: | Acyl-coenzyme A thioesterase |
| UniProt Gene Name: | ACOT1 |
| UniProt Entry Name: | ACOT1_HUMAN |
