Description
| Antibody Name: | ACKR4 Antibody |
| Antibody SKU: | PACO00543 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IF:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | synthesized peptide derived from the N-terminal region of human CCRL1. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | CCRL1; CCBP2; CCR11; VSHK1; C-C chemokine receptor type 11; C-C CKR-11; CC-CKR-11; CCR-11; CC chemokine receptor-like 1; CCRL1; CCX CKR |
| UniProt Protein Function: | CCRL1: Receptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 3q22 Cellular Component: early endosome; integral to plasma membrane; plasma membrane; recycling endosome Molecular Function:chemokine binding; chemokine receptor activity; protein binding; scavenger receptor activity Biological Process: chemotaxis; G-protein coupled receptor protein signaling pathway; immune response; receptor-mediated endocytosis |
| NCBI Summary: | The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9NPB9 |
| NCBI GenInfo Identifier: | 14285406 |
| NCBI Gene ID: | 51554 |
| NCBI Accession: | Q9NPB9.1 |
| UniProt Secondary Accession: | Q9NPB9,B2R9U7, |
| UniProt Related Accession: | Q9NPB9 |
| Molecular Weight: | |
| NCBI Full Name: | Atypical chemokine receptor 4 |
| NCBI Synonym Full Names: | atypical chemokine receptor 4 |
| NCBI Official Symbol: | ACKR4 |
| NCBI Official Synonym Symbols: | PPR1; CCBP2; CCR10; CCR11; CCRL1; VSHK1; CCR-11; CKR-11; CCX CKR; CCX-CKR; CC-CKR-11 |
| NCBI Protein Information: | atypical chemokine receptor 4 |
| UniProt Protein Name: | Atypical chemokine receptor 4 |
| UniProt Synonym Protein Names: | C-C chemokine receptor type 11; C-C CKR-11; CC-CKR-11; CCR-11; CC chemokine receptor-like 1; CCRL1; CCX CKR |
| UniProt Gene Name: | ACKR4 |
| UniProt Entry Name: | ACKR4_HUMAN |