Acetyl-Histone H4-K12 Monoclonal Antibody (CAB23683)
- SKU:
- CAB23683
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
- Applications:
- IP
Description
| Product Name: | Acetyl-Histone H4-K12 Monoclonal Antibody |
| Product Code: | CAB23683 |
| Reactivity: | Human, Mouse, Rat, Other (Wide Range) |
| Applications: | Immunohistochemistry, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57733 |
| Reactivity: | Human, Mouse, Rat, Other (Wide Range) |
| Tested Applications: | IHC-P, IP, ChIP, ELISA |
| Key Applications: | Immunohistochemistry, Immunoprecipitation |
| Recommended Dilution: | CHIP 1:50-1:100, IHC-P 1:500-1:1000, IP 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa |
| Cellular Location: | Chromosome, Nucleus |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
| Immunogen: | A synthetic acetylated peptide around K12 of human Histone H4 (NP_003486.1). |
| Sequence: | MSGRG KGGKG LGKGG AKRHR KVLRD NIQGI TKPAI RRLAR RGGVK RISGL IYEET RGVLK VFLEN VIRDA VTYTE HAKRK TVTAM DVVYA LKRQG RTLYG |
| Synonyms: | H4/I, H4C1, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4FI, H4-16, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, HIST1H4B |
| Calculated MW: | 11kDa |
| Observed MW: | 11kDa |
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