Acetyl-Histone H3-K4/K9/K14/K18/K23/K27 Polyclonal Antibody

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SKU:
CAB21295
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:Acetyl-Histone H3-K4/K9/K14/K18/K23/K27 Polyclonal Antibody
Product Code:CAB21295
Reactivity:Human, Mouse, Rat, Other (Wide Range)
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human, Mouse, Rat, Other (Wide Range)
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:HeLa nuclear extract, NIH/3T3 nuclear extract, C6 nuclear extract, H3 protein
Cellular Location:Chromosome, Nucleus

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Immunogen:A synthetic acetylated peptide around K4 & K27 of human Acetyl-Histone H3-K4/K9/K14/K18/K23/K27 (NP_003520.1).
Sequence:TKQTA RKSTG GKAPR KQLAT KAAR
Synonyms:H3/A, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, H3C10, H3C11, H3C12, HIST1H3A
Calculated MW:15kDa
Observed MW:17kDa
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